CFN Funded ProjectsProducts
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| Statin therapy and mortality among new long-term care residents in Ontario, Canada: the contribution of clinical assessment data to a population-based cohort studyPoster presentation at International Population Data Linkage Conference (IPDLN), Wales, United Kingdom, August 24-26, 2016. (I)
Abstract published in International Journal for Population Data Science 2017;1(1): apr. 2017.SIG2014-M1 University of Waterloo, Mt. Sinai Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2016-08-25 | | | The identification of frailty and its role as an effect modifier of adverse drug-related outcomes among assisted living residents. Stock K, Hogan DB, Tyas S, Bronskill SE, Morris AM, Bell CM, Jeffs L, Maxwell CJ. The identification
of frailty and its role as an effect modifier of adverse drug-related outcomes among assisted living
residents.
Oral presentation, 44th Annual Scientific & Educational Meeting, Canadian Association on
Gerontology, Calgary, AB, Oct 23-25, 2015.
Abstract published in C J Aging
SIG2014-M1 University of Calgary, ICES (Institute for Clincial Evaluative Sciences), Mt. Sinai Hospital, St. Michael's Hospital, University of Waterloo | Publication | 2015-10-23 | | | Potentially Inappropriate Medication Use in Long-Term Care: Preliminary Findings from a Qualitative Analysis Poster presentation at CFN Annual Meeting April 22, 2017, Toronto, ON, CanadaSIG2014-M1 St. Michael's Hospital, Mt. Sinai Hospital, ICES (Institute for Clincial Evaluative Sciences), University of Waterloo | Publication | 2017-04-22 | | | Going beyond antimicrobial stewardship to identify outliers in drug prescribing: a protocol for a cohort study of frail older adultsPoster presentation at CFN annual meeting, April 22, 2017, Toronto, ON, CanadaSIG2014-M1 Mt. Sinai Hospital, University of Toronto, St. Michael's Hospital, University of Waterloo, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2017-04-22 | | | Influences on the start, selection and duration of treatment with antibiotics in long-term care facilitiesAntibiotic prescribers exhibit individual, measurable, historical tendencies towards antibiotic initiation, use of prolonged treatment duration and class selection; prescriber audit-and-feedback may be a promising tool to optimize antibiotic use in long-term care.SIG2014-M1 University of Toronto, Mt. Sinai Hospital, University of Waterloo, St. Michael's Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2017-06-26 | | | Prescriber tendencies influence antibiotic initiation, selection and duration in long term care facilitiesPoster presentation at the AMMI Canada – CACMID Annual Conference 2017, Toronto, ON, May 4-6, 2017.
Abstract published in Journal of the Association of Medical Microbiology and Infectious Disease Canada 2017;Supplement:105.SIG2014-M1 University of Toronto, Mt. Sinai Hospital, University of Waterloo, St. Michael's Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2017-05-04 | | | Prescriber tendencies influence antibiotic initiation, selection and duration in long term care facilitiesAbstract published in Journal of the Association of Medical Microbiology and Infectious Disease Canada 2017;Supplement:105.SIG2014-M1 University of Toronto, Mt. Sinai Hospital, University of Waterloo, St. Michael's Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2017-05-03 | | | Frailty, drug use and hospitalization among older assisted living residentsPoster presentation, 3rd Annual TVN Conference on improving care for frail elderly Canadians, Toronto, ON, Sept 27-29, 2015.SIG2014-M1 University of Calgary, ICES (Institute for Clincial Evaluative Sciences), Mt. Sinai Hospital, St. Michael's Hospital, University of Waterloo | Publication | 2015-09-27 | | | Frailty and recognizing appropriate medications in geriatrics and long term care [FRAMING-LTC]: Protocol. Poster presentation, 3rd Annual TVN Conference on improving care for frail elderly Canadians, Toronto, ON, Sept 27-29, 2015.SIG2014-M1 St. Michael's Hospital, Mt. Sinai Hospital, ICES (Institute for Clincial Evaluative Sciences), University of Waterloo | Publication | 2015-09-27 | | | Exposure to potentially inappropriate medication among long-term care residents with cognitive impairment in Ontario: Is therePoster presentation at Alzheimer’s Association International Conference (AAIC), Toronto, ON, July 24-28, 2016.
Abstract published in Journal of Alzheimer's association 2016;12(7):578SIG2014-M1 University of Waterloo, Queen's University, University of Toronto, University of Calgary, Mt. Sinai Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2016-07-24 | | | Antipsychotic use and hospitalization among older assisted living residents: Does risk vary by frailty status? There is emerging interest regarding whether an assessment of frailty may help to better differentiate both the potential risks as well as benefits of medications in older adults. We showed that two different approaches to defining frailty (the frailty index and physical phenotype) showed similar findings in modifying the risk of hospitalization associated with prevalent antipsychotic use among older Assisted Living residents. Not only was risk elevated among frail antipsychotic users, hospitalization risk was significantly lower for users of antipsychotics among non-frail residents.SIG2014-M1 University of Calgary, University of Massachusetts, Canadian Institute for Health Information (CIHI), ICES (Institute for Clincial Evaluative Sciences), Mt. Sinai Hospital, St. Michael's Hospital, University of Waterloo | Publication | 2017-07-01 | | | The variation of statin use among nursing home residents and physicians: a cross-sectional analysis. Statin prescribing was substantial within nursing homes, even among frail residents. After controlling for resident characteristics, the prescribing of statins was not randomly distributed across physicians. Further studies are required to evaluate the risks and benefits of statin use, and discontinuation, among nursing home residents to inform clinical practice in this setting.SIG2014-M1 University of Waterloo, Mt. Sinai Hospital, University of Toronto, St. Michael's Hospital, University of Calgary, University of Massachusetts, Queen's University, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2017-09-01 | "M. Campitelli ", Colleen Maxwell, "V. Giannakeas ", Chaim Bell, Nick Daneman, Lianne Jeffs, Andrew Morris, "PC Austin ", David Hogan, "DT Ko ", Kate Lapane, "LC. Maclagan ", Dallas Seitz, Susan Bronskill | | Antipsychotic use, frailty and health outcomes among residents of assisted living.Oral presentation at 32rd International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE).
Abstract published in Pharmacoepidemiology and Drug Safety 2016;25(Suppl. 3):263.SIG2014-M1 University of Waterloo, Canadian Institute for Health Information (CIHI), University of Massachusetts, ICES (Institute for Clincial Evaluative Sciences), Mt. Sinai Hospital, St. Michael's Hospital, University of Calgary | Publication | 2016-08-28 | | | Conditions and factors associated with potentially inappropriate medication use in frail older adults: a mixed methods analysis in long-term care.Poster presentation at Canadian Association of Health Services & Policy Research (CAHSPR) Conference, Toronto, ON, May 24-26, 2017. SIG2014-M1 St. Michael's Hospital, University of Waterloo, Mt. Sinai Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2017-05-24 | | | Survival among older residents of nursing homes prescribed intensive-dose and moderate-dose statins: a propensity-score matched cohort studyGiven the absence of a survival advantage for those receiving intensive-dose statins compared to moderate-dose statins in long-term care, it may be prudent to reduce statin doses for specific residents of nursing homes at increased risk of statin-related adverse events.SIG2014-M1 University of Waterloo, Mt. Sinai Hospital, St. Michael's Hospital, University of Massachusetts, University of Toronto, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2018-03-31 | | | Survival among residents of nursing homes aged 75 years and older prescribed intensive-dose and moderate-dose statins: a propensity-score matched cohort studyAccepted for oral presentation to Canadian Association of Health Services & Policy Research (CAHSPR) Conference, May 28-31, 2018, Montreal, QCSIG2014-M1 University of Waterloo, Mt. Sinai Hospital, St. Michael's Hospital, University of Massachusetts, University of Toronto, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2018-05-28 | | | Frailty and potentially inappropriate medication use at nursing home transitionMany residents with cognitive impairment or dementia enter nursing homes on potentiall inappropriate medications (PIMs). PIMs are more likely to be started in frail individuals following admission. Interventions to support deprescribing of PIMs should be implemented targeting frail individuals during the transition to nursing home.SIG2014-M1 University of Waterloo, Mt. Sinai Hospital, University of Calgary, University of Toronto, Queen's University, St. Michael's Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2017-10-01 | "LC. Maclagan ", Colleen Maxwell, "S. Gandhi ", "J. Guan ", Chaim Bell, David Hogan, Nick Daneman, Sudeep Gill, Andrew Morris, Lianne Jeffs, "M. Campitelli ", Dallas Seitz, Susan Bronskill | | Risk of fall-related injuries in residents of nursing homes receiving low-dose trazodone compared to benzodiazepines: a matched cohort studyWe found that new use of low-dose trazodone was no safer than new use of benzodiazepines in protecting against fall-related injuries in Ontario nursing homes. In Canada, nursing homes care for a particularly frail population of older adults. When our study findings are jointly considered with rising trends in the use of low-dose trazodone in Ontario nursing homes, our findings suggest that increased vigilance related to off-label substitution of trazodone for other psychotropic drug therapies is recommended.SIG2014-M1 ICES (Institute for Clincial Evaluative Sciences), Mt. Sinai Hospital, St. Michael's Hospital, University of Waterloo | Publication | 2018-03-31 | Susan Bronskill, "Michael Campitelli ", "A. Iaboni ", "N. Herrmann ", "J. Guan ", "L. Maclagan ", "J. Watt ", "P. Rochon ", Andrew Morris, Lianne Jeffs, Chaim Bell, Colleen Maxwell | | Risk of fall-related injuries in residents of nursing homes receiving low-dose trazodone compared to benzodiazepines: a matched cohort studyAccepted for oral presentation to Canadian Association of Health Services & Policy Research (CAHSPR) Conference, May 28-31, 2018, Montreal, QCSIG2014-M1 ICES (Institute for Clincial Evaluative Sciences), Mt. Sinai Hospital, St. Michael's Hospital, University of Waterloo | Publication | 2018-04-04 | Susan Bronskill, "M. Campitelli ", "A. Iaboni ", "N. Herrmann ", "J. Guan ", "L. Maclagan ", "J. Watt ", "PA Rochon ", Andrew Morris, Lianne Jeffs, Chaim Bell, Colleen Maxwell | | Exposure to potentially inappropriate medication among long-term care residents with cognitive impairment in Ontario: Is there an association with frailty? Oral presentation to Canadian Association for Health Services and Policy Research (CAHSPR), May 9-12, 2016. Toronto, ONSIG2014-M1 University of Waterloo, Queen's University, University of Toronto, University of Calgary, Mt. Sinai Hospital, ICES (Institute for Clincial Evaluative Sciences) | Publication | 2016-05-09 | "L. Maclagan ", "J. Guan ", "S. Gandhi ", Colleen Maxwell, "M. Campitelli ", Sudeep Gill, Nick Daneman, Dallas Seitz, David Hogan, Andrew Morris, Chaim Bell, Susan Bronskill |
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